信息8296:
2014; 111 918 926
clomid Suitable monovalent substituents on a substitutable carbon atom of an optionally substituted group are independently halogen; CH 2 0 4 R; CH 2 0 4 OR; O CH 2 0 4 R, O CH 2 0 4 C O OR; CH 2 0 4 CH OR 2; CH 2 0 4 SR; CH 2 0 4 Ph, which may be substituted with R; CH 2 0 4 O CH 2 0 1 Ph which may be substituted with R; CH CHPh, which may be substituted with R; CH 2 0 4 O CH 2 0 1 pyridyl which may be substituted with R; NO 2; CN; N 3; CH 2 0 4 N R 2; CH 2 0 4 N R C O R; N R C S R; CH 2 0 4 N R C O NR 2; N R C S NR 2; CH 2 0 4 N R C O OR; N R N R C O R; N R N R C O NR 2; N R N R C O OR; CH 2 0 4 C O R; C S R; CH 2 0 4 C O OR; CH 2 0 4 C O SR; CH 2 0 4 C O OSiR 3; CH 2 0 4 OC O R; OC O CH 2 0 4 SR, SC S SR; CH 2 0 4 SC O R; CH 2 0 4 C O NR 2; C S NR 2; C S SR; CH 2 0 4 OC O NR 2; C O N OR R; C O C O R; C O CH 2 C O R; C NOR R; CH 2 0 4 SSR; CH 2 0 4 S O 2 R; CH 2 0 4 S O 2 OR; CH 2 0 4 OS O 2 R; S O 2 NR 2; CH 2 0 4 S O R; CH 2 0 4 S O NR R; N R S O 2 NR 2; N R S O 2 R; N R S O NR R 2; N OR R; N S O R 2; N OR SO 2 R; C NH NR 2; P O 2 R; P O R 2; OP O R 2; OP O OR 2; SiR 3; C 1 4 straight or branched alkylene O N R 2; or C 1 4 straight or branched alkylene C O O N R 2, wherein each R may be substituted as defined below and is independently hydrogen, C 1 6 aliphatic, CH 2 Ph, O CH 2 0 1 Ph, CH 2 5 6 membered heteroaryl ring, or a 5 6 membered saturated, partially unsaturated, or aryl ring having 0 4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or, notwithstanding the definition above, two independent occurrences of R, taken together with their intervening atom s, form a 3 12 membered saturated, partially unsaturated, or aryl mono or bicyclic ring having 0 4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, which may be substituted as defined below